Clinical Studies

No. Diagnosis Title Author(s) Year Medication(s) Design Major Outcome(s)
91 - “The effect of five day dosing with THCV on THC-induced cognitive, psychological and physiological effects in healthy male human volunteers: A placebo-controlled, double-blind, crossover pilot trial.” Atakan Z,
Englund A,
Kralj A,
Morrison P,
Murray R,
Tunstall N
2015 Delta-9-THC Controlled Study Inhibition of some of the well-known effects of THC by THCV and potentiation of other effects
92 - Acute effects of delta-9-tetrahydrocannabinol, cannabidiol and their combination on facial emotion recognition: a randomised, double-blind, placebo-controlled study in cannabis users. Curran HV,
Das RK,
Freeman TP,
Gardener C,
Hindocha C,
Morgan CJ,
Schafer G
2015 Cannabidiol,
Cannabis,
Delta-9-THC
Controlled Study Improvement of recognition of emotional facial affect by CBD and attenuation of the impairment induced by THC
93 Alzheimer's disease Tetrahydrocannabinol for neuropsychiatric symptoms in dementia: A randomized controlled trial. Ahmed AI,
Feuth T,
Kramers C,
Olde Rikkart MG,
Rosenberg PB,
van der Marck MA,
var den Elsen GA,
Verkes RJ
2015 Delta-9-THC,
Cannabis,
Delta-9-THC
Controlled Study No reduction in NPS by low-dose THC (3x1.5mg), though it is well-tolerated
94 Dependency/withdrawal,
Pain
The prescription of medical cannabis by a transitional pain service to wean a patient with complex pain from opioid use following liver transplantation: a case report. Clarke H,
Ghanekar A,
Hanlon JG,
Katznelson R,
McGilvray I,
Meng H
2015 Cannabis,
Cannabis,
Delta-9-THC
Uncontrolled case report The use of cannabis reduced opioid consumption
95 Pain Single dose delta-9-tetrahydrocannabinol in chronic pancreatitis patients: analgesic efficacy, pharmacokinetics and tolerability de Vries M,
Pain and Nociception Neuroscience Research Group,
van Goor H,
van Rijckevorsel DC,
Vissers KC,
Wilder-Smith OH
2015 Delta-9-THC,
Cannabis,
Delta-9-THC
Controlled Study No effect of a single low dose of THC on abdominal pain resulting from chronic pancreatitis in clinical study.
96 Appetite loss/weight loss,
Cancer,
Nausea/vomiting,
Pain
Improving Quality of Life With Nabilone During Radiotherapy Treatments for Head and Neck Cancers: A Randomized Double-Blind Placebo-Controlled Trial Côté M,
Fortin A,
Trudel M,
Wang C
2015 Nabilone,
Cannabis,
Delta-9-THC
Controlled Study Nabilone did not reduce pain and nausea in patients treated for head and neck cancer.
97 Cancer,
Nausea/vomiting
Dronabinol Treatment of Refractory Nausea and Vomiting Related to Peritoneal Carcinomatosis. Hernandez SL,
Sheyner I,
Stewert JT,
Stover KT
2015 Delta-9-THC,
Cannabis,
Delta-9-THC
Open Study THC may be very effective in the treatment of nausea and vomiting in end-stage cancer.
98 Cancer Patterns of Use of Medical Cannabis Among Israeli Cancer Patients: A Single Institution Experience. Garty M,
Lesham Y,
Urban D,
Waissengrin B,
Wolf I
2015 Cannabis,
Cannabis,
Delta-9-THC
Open Study Cannabis use “is perceived as highly effective” by some patients with advanced cancer.
99 HIV/AIDS High-intensity cannabis use associated with lower plasma human immunodeficiency virus-1 RNA viral load among recently infected people who use injection drugs. Guillemi S,
Hogg R,
Kerr T,
Marshall B,
Milloy MJ,
Montaner JS,
Richardson L,
Wood E
2015 Cannabis,
Cannabis,
Delta-9-THC
Open Study At least daily cannabis use was associated with significant lower plasma HIV viral loads.
100 Pain Experience of adjunctive cannabis use for chronic non-cancer pain: Findings from the Pain and Opioids IN Treatment (POINT) study. Bruno R,
Campbell G,
Cohen M,
Degenhardt L,
Farrell M,
Hall WD,
Lintzeris N
2015 Cannabis,
Cannabis,
Delta-9-THC
Survey Pain patients, who receive opioids, experience better pain relief if they also take cannabis.

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