Clinical Studies

No. Diagnosis Title Author(s) Year Medication(s) Design Major Outcome(s)
1 Pain Cannabinoid-opioid interaction in chronic pain Abrams DI,
Benowitz NL,
Couey P,
Kelly ME,
Shade SB
2011 Cannabis Open Study Pain was significantly decreased
2 HIV/AIDS A pilot study of the effects of cannabis on appetite hormones in HIV-infected adult men. Ellis RJ,
Gouaux B,
Grant I,
Riggs PK,
Rossi SS,
Sorkin LS,
Vaida F
2011 Cannabis Controlled Study Cannabis modulates the concentration of appetite hormones
3 Diarrhoea,
Gastrointestinal disorder,
Inflammation
Treatment of Crohn’s disease with cannabis: an observational study. Half E,
Konikoff FM,
Lev LB,
Naftali T,
Yablekovitz D
2011 Cannabis Open Study Of the 30 patients 21 improved significantly
4 Posttraumatic stress disorder Medical cannabis use in post-traumatic stress disorder: a naturalistic observational study. Reznik I. 2011 Cannabis Open Study In most cases a significant improvement in quality of life and pain, with some positive changes in severity of posttraumatic stress disorder was observed.
5 Tourette's syndrome Cannabinoids improve driving ability in a Tourette’s patient. Brunnauer A,
Dehning S,
Laux G,
Müller N,
Segmiller FM,
Volkamer T
2011 Delta-9-THC Uncontrolled case report THC improved driving ability
6 Cancer Spontaneous regression of septum pellucidum/forniceal pilocytic astrocytomas-possible role of Cannabis inhalation. Foroughi M,
Hendson G,
Sargent MA,
Steinbok P.
2011 Cannabis Uncontrolled case report Spontaneous regression of benign brain tumour may have been associated with cannabis use.
7 Pain Cannabis use in patients with fibromyalgia: effect on symptoms relief and health-related quality of life. Capellà D,
Carbonell J,
Durán M,
Farré M,
Fiz J
2011 Cannabis Open Study The use of cannabis was associated with reduction of some fibromyalgia symptoms.
8 Anxiety Neural basis of anxiolytic effects of cannabidiol (CBD) in generalized social anxiety disorder: a preliminary report. Atakan Z,
Bhattacharyya S,
Busatto GF,
Crippa JA,
Derenusson GN,
Duran FL,
Ferrari TB,
Freitas-Ferrari MC,
Fusar-Poli P,
Hallak JE,
Martín-Santos R,
McGuire PK,
Santos Filho A,
Simões MV,
Wichert-Ana L,
Zuardi AW
2011 Cannabidiol Controlled Study CBD reduces anxiety in patients with generalized social anxiety disorder.
9 Anxiety Cannabidiol Reduces the Anxiety Induced by Simulated Public Speaking in Treatment-Naïve Social Phobia Patients. Bergamaschi MM,
Chagas MH,
Crippa JA,
De Martinis BS,
de Oliveira DC,
Hallak JE,
Kapczinski F,
Martín-Santos R,
Nardi AE,
Queiroz RH,
Quevedo J,
Roesler R,
Schröder N,
Zuardi AW
2011 Cannabidiol Controlled Study Cannabidiol significamtly reduced anxiety.
10 Appetite loss/weight loss; Cancer Delta-9-tetrahydrocannabinol may palliate altered chemosensory perception in cancer patients: results of a randomized, double-blind, placebo-controlled pilot trial. Baracos VE,
Brisbois TD,
Chasen M,
de Kock IH,
Lamoureux DC,
Macdonald N,
Mirhosseini M,
Watanabe SM,
Wismer WV.
2011 Delta-9-THC Controlled Study THC improved taste and appetite

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